JIIT

Academic Experts

Prof. Shweta Dang

Professor

shweta.dang@jiit.ac.in

Biography

Dr Shweta Dang is working in Dept of biotechnology JIIT Noida since 2009.Prior to joining JIIT she was working as a Research Scientist in Formulation Research and Development, Jubilant Organosys Ltd, NOIDA for US and EU regulatory markets for ANDA filings. She has also qualified P.G. Diploma, Patent Law, NALSAR University, Hyderabad and is a lifetime member of IPA (Indian Pharmaceutical Association). She is working in novel and targeted drug delivery. Her research work is focused on the nose to brain delivery of drugs and synergistic combinations for anti-cancer drugs and CNS drugs. She is an active researcher and has published her work in various journals of national and international repute, reflected by more than 5600 citations and a H-index of 30. She has been awarded several extramural funding’s from various government agencies as a principal investigator. She has been granted 3 Indian Patents on her research work.

Research Highlights

Research Highlights : • Intranasal Drug Delivery Systems

Investigating intranasal routes for the effective delivery of anti-epileptic, anti-Alzheimer’s, and psychiatric medications, with a focus on bypassing the blood-brain barrier for rapid and targeted central nervous system (CNS) action.

• Nose-to-Brain Drug Delivery via Nano-formulations

Exploring the direct nose-to-brain pathway using nanocarriers in animal models to enhance CNS drug targeting and bioavailability.

• Drug Repurposing and Synergistic Combinations for Cancer Therapy

Identifying synergistic drug combinations and evaluating the anti-cancer potential of repurposed pharmaceuticals to develop novel, multi-targeted therapies.

• Nano-formulation Development for Enhanced Drug Delivery

Designing and optimizing nanotechnology-based formulations to improve the solubility, stability, and therapeutic efficacy of both single drugs and combination regimens.

• Surface-Modified Nanocarriers for Targeted Drug Delivery

Developing surface-engineered nanoparticles for site-specific delivery, aiming to reduce systemic side effects and enhance therapeutic outcomes in various disease models

Areas Of Interest

Novel and targeted drug delivery systems

Publications

• Garima Rai, Pammi Gauba, Amit Tyagi, Shweta Dang , Lactoferrin-modified PLGA nanoparticles for pregabalin: development, characterization, in vitro targeting and pharmacodynamic evaluation, Drug Delivery and Translational Research, 2025, 1-19 (IF 5.5)
• Surbhi Sharma, Pammi Gauba, Amit Tyagi, Shweta Dang, Chitosan-modified polymeric nanoparticles for the nose-to-brain drug delivery of paroxetine: an in vitro and in vivo evaluation, Nanoscale, 2025, 17(3), 1687-1702 (IF 5.1)
• Surbhi Sharma, Amit Tyagi, Shweta Dang, Nose to Brain Delivery of Transferrin conjugated PLGA nanoparticles for clonidine, International Journal of Biological Macromolecules, Volume 252,2023,126471, ISSN 0141-8130. Scopus (IF 8.2)
• Surbhi Sharma, Shweta Dang, Polysorbate 80 surface modified PLGA nanoparticles: an in-vitro evaluation of cellular uptake and cytotoxicity on neuro-2a cells, Journal of Microencapsulation, 2023 Aug 23;1-15. Scopus (IF 4.2)
• Pallavi Kumari, Shweta Dang, Dual drug loaded nanostructured lipid carrier for cytotoxic effect against breast cancer-a drug repurposing approach., Surfaces and Interfaces, 2023, 103138, ISSN 2468-0230. Scopus (IF 6.2)